Identification of recurrent focal copy number variations and their putative targeted driver genes in ovarian cancer

BACKGROUND: Genomic regions with recurrent DNA copy number variations (CNVs) are generally believed to encode oncogenes and tumor suppressor genes (TSGs) that drive cancer growth. However, it remains a challenge to delineate the key cancer driver genes from the regions encoding a large number of gen...

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Detalles Bibliográficos
Autores principales: Zhang, Liangcai, Yuan, Ying, Lu, Karen H., Zhang, Li
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Methodology Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4881176/
https://www.ncbi.nlm.nih.gov/pubmed/27230211
http://dx.doi.org/10.1186/s12859-016-1085-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4881176/
https://www.ncbi.nlm.nih.gov/pubmed/27230211
http://dx.doi.org/10.1186/s12859-016-1085-7

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