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Identification of recurrent focal copy number variations and their putative targeted driver genes in ovarian cancer
BACKGROUND: Genomic regions with recurrent DNA copy number variations (CNVs) are generally believed to encode oncogenes and tumor suppressor genes (TSGs) that drive cancer growth. However, it remains a challenge to delineate the key cancer driver genes from the regions encoding a large number of gen...
Autores principales: | Zhang, Liangcai, Yuan, Ying, Lu, Karen H., Zhang, Li |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4881176/ https://www.ncbi.nlm.nih.gov/pubmed/27230211 http://dx.doi.org/10.1186/s12859-016-1085-7 |
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