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Creating Patient-Specific Neural Cells for the In Vitro Study of Brain Disorders

As a group, we met to discuss the current challenges for creating meaningful patient-specific in vitro models to study brain disorders. Although the convergence of findings between laboratories and patient cohorts provided us confidence and optimism that hiPSC-based platforms will inform future drug...

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Detalles Bibliográficos
Autores principales: Brennand, Kristen J., Marchetto, M. Carol, Benvenisty, Nissim, Brüstle, Oliver, Ebert, Allison, Izpisua Belmonte, Juan Carlos, Kaykas, Ajamete, Lancaster, Madeline A., Livesey, Frederick J., McConnell, Michael J., McKay, Ronald D., Morrow, Eric M., Muotri, Alysson R., Panchision, David M., Rubin, Lee L., Sawa, Akira, Soldner, Frank, Song, Hongjun, Studer, Lorenz, Temple, Sally, Vaccarino, Flora M., Wu, Jun, Vanderhaeghen, Pierre, Gage, Fred H., Jaenisch, Rudolf
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4881284/
https://www.ncbi.nlm.nih.gov/pubmed/26610635
http://dx.doi.org/10.1016/j.stemcr.2015.10.011