Crystal structure of the Rous sarcoma virus intasome

Integration of the reverse-transcribed viral DNA into the host genome is an essential step in the lifecycle of retroviruses. Retrovirus integrase (IN) catalyzes insertions of both ends of the linear viral DNA into a host chromosome (1). IN from HIV-1 and closely related retroviruses share the three-...

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Detalles Bibliográficos
Autores principales: Yin, Zhiqi, Shi, Ke, Banerjee, Surajit, Pandey, Krishan K., Bera, Sibes, Grandgenett, Duane P., Aihara, Hideki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4881392/
https://www.ncbi.nlm.nih.gov/pubmed/26887497
http://dx.doi.org/10.1038/nature16950

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4881392/
https://www.ncbi.nlm.nih.gov/pubmed/26887497
http://dx.doi.org/10.1038/nature16950

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