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Crystal structure of the Rous sarcoma virus intasome
Integration of the reverse-transcribed viral DNA into the host genome is an essential step in the lifecycle of retroviruses. Retrovirus integrase (IN) catalyzes insertions of both ends of the linear viral DNA into a host chromosome (1). IN from HIV-1 and closely related retroviruses share the three-...
Autores principales: | Yin, Zhiqi, Shi, Ke, Banerjee, Surajit, Pandey, Krishan K., Bera, Sibes, Grandgenett, Duane P., Aihara, Hideki |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4881392/ https://www.ncbi.nlm.nih.gov/pubmed/26887497 http://dx.doi.org/10.1038/nature16950 |
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