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The Folding of de Novo Designed Protein DS119 via Molecular Dynamics Simulations

As they are not subjected to natural selection process, de novo designed proteins usually fold in a manner different from natural proteins. Recently, a de novo designed mini-protein DS119, with a βαβ motif and 36 amino acids, has folded unusually slowly in experiments, and transient dimers have been...

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Detalles Bibliográficos
Autores principales: Wang, Moye, Hu, Jie, Zhang, Zhuqing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4881441/
https://www.ncbi.nlm.nih.gov/pubmed/27128902
http://dx.doi.org/10.3390/ijms17050612