Copper Homeostasis as a Therapeutic Target in Amyotrophic Lateral Sclerosis with SOD1 Mutations

Amyotrophic lateral sclerosis (ALS) is a lethal neurodegenerative disease affecting both upper and lower motor neurons, and currently, there is no cure or effective treatment. Mutations in a gene encoding a ubiquitous antioxidant enzyme, Cu,Zn-superoxide dismutase (SOD1), have been first identified...

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Detalles Bibliográficos
Autores principales: Tokuda, Eiichi, Furukawa, Yoshiaki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2016
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4881462/
https://www.ncbi.nlm.nih.gov/pubmed/27136532
http://dx.doi.org/10.3390/ijms17050636

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4881462/
https://www.ncbi.nlm.nih.gov/pubmed/27136532
http://dx.doi.org/10.3390/ijms17050636

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