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3D-QSAR Studies on Barbituric Acid Derivatives as Urease Inhibitors and the Effect of Charges on the Quality of a Model

Urease enzyme (EC 3.5.1.5) has been determined as a virulence factor in pathogenic microorganisms that are accountable for the development of different diseases in humans and animals. In continuance of our earlier study on the helicobacter pylori urease inhibition by barbituric acid derivatives, 3D-...

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Detalles Bibliográficos
Autores principales: Ul-Haq, Zaheer, Ashraf, Sajda, Al-Majid, Abdullah Mohammed, Barakat, Assem
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4881483/
https://www.ncbi.nlm.nih.gov/pubmed/27144563
http://dx.doi.org/10.3390/ijms17050657