12-Lipoxygenase Inhibition on Microalbuminuria in Type-1 and Type-2 Diabetes Is Associated with Changes of Glomerular Angiotensin II Type 1 Receptor Related to Insulin Resistance

(1) Background: 12-lipoxygenase (12-LO) is involved in the development of diabetic nephropathy (DN). In the present study, we investigated whether 12-LO inhibition may ameliorate type-2 DN (T2DN) by interfering with insulin resistance (IR); (2) Methods: Rat glomerular mesangial cells, glomeruli and...

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Detalles Bibliográficos
Autores principales: Xu, Hong-Zhao, Cheng, Yan-Li, Wang, Wan-Ning, Wu, Hao, Zhang, Yuan-Yuan, Zang, Chong-Sen, Xu, Zhong-Gao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4881510/
https://www.ncbi.nlm.nih.gov/pubmed/27164093
http://dx.doi.org/10.3390/ijms17050684

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4881510/
https://www.ncbi.nlm.nih.gov/pubmed/27164093
http://dx.doi.org/10.3390/ijms17050684

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