Connecting the Dots: From DNA Damage and Repair to Aging

Mammalian cells evolve a delicate system, the DNA damage response (DDR) pathway, to monitor genomic integrity and to prevent the damage from both endogenous end exogenous insults. Emerging evidence suggests that aberrant DDR and deficient DNA repair are strongly associated with cancer and aging. Our...

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Detalles Bibliográficos
Autores principales: Pan, Mei-Ren, Li, Kaiyi, Lin, Shiaw-Yih, Hung, Wen-Chun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2016
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4881511/
https://www.ncbi.nlm.nih.gov/pubmed/27164092
http://dx.doi.org/10.3390/ijms17050685

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4881511/
https://www.ncbi.nlm.nih.gov/pubmed/27164092
http://dx.doi.org/10.3390/ijms17050685

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