Cell and Signal Components of the Microenvironment of Bone Metastasis Are Affected by Hypoxia

Bone metastatic cells release bone microenvironment proteins, such as the matricellular protein SPARC (secreted protein acidic and rich in cysteine), and share a cell signaling typical of the bone metabolism controlled by Runx2. The megakaryocytes in the bone marrow engrafted by the metastases seem...

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Detalles Bibliográficos
Autores principales: Bendinelli, Paola, Maroni, Paola, Matteucci, Emanuela, Desiderio, Maria Alfonsina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2016
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4881528/
https://www.ncbi.nlm.nih.gov/pubmed/27187355
http://dx.doi.org/10.3390/ijms17050706

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4881528/
https://www.ncbi.nlm.nih.gov/pubmed/27187355
http://dx.doi.org/10.3390/ijms17050706

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