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Cell and Signal Components of the Microenvironment of Bone Metastasis Are Affected by Hypoxia
Bone metastatic cells release bone microenvironment proteins, such as the matricellular protein SPARC (secreted protein acidic and rich in cysteine), and share a cell signaling typical of the bone metabolism controlled by Runx2. The megakaryocytes in the bone marrow engrafted by the metastases seem...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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MDPI
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4881528/ https://www.ncbi.nlm.nih.gov/pubmed/27187355 http://dx.doi.org/10.3390/ijms17050706 |