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Novel Omega-3 Fatty Acid Epoxygenase Metabolite Reduces Kidney Fibrosis

Cytochrome P450 (CYP) monooxygenases epoxidize the omega-3 polyunsaturated fatty acid (PUFA) docosahexaenoic acid into novel epoxydocosapentaenoic acids (EDPs) that have multiple biological actions. The present study determined the ability of the most abundant EDP regioisomer, 19,20-EDP to reduce ki...

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Detalles Bibliográficos
Autores principales: Sharma, Amit, Khan, Md. Abdul Hye, Levick, Scott P., Lee, Kin Sing Stephen, Hammock, Bruce D., Imig, John D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4881572/
https://www.ncbi.nlm.nih.gov/pubmed/27213332
http://dx.doi.org/10.3390/ijms17050751