Downregulation of Runx2 by 1,25-Dihydroxyvitamin D(3) Induces the Transdifferentiation of Osteoblasts to Adipocytes

1,25-Dihydroxyvitamin D(3) (1,25(OH)(2)D(3)) indirectly stimulates bone formation, but little is known about its direct effect on bone formation. In this study, we observed that 1,25(OH)(2)D(3) enhances adipocyte differentiation, but inhibits osteoblast differentiation during osteogenesis. The posit...

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Detalles Bibliográficos
Autores principales: Kim, Jung Ha, Seong, Semun, Kim, Kabsun, Kim, Inyoung, Jeong, Byung-Chul, Kim, Nacksung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4881589/
https://www.ncbi.nlm.nih.gov/pubmed/27213351
http://dx.doi.org/10.3390/ijms17050770

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4881589/
https://www.ncbi.nlm.nih.gov/pubmed/27213351
http://dx.doi.org/10.3390/ijms17050770

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