Angiotensin II Stimulation of DPP4 Activity Regulates Megalin in the Proximal Tubules

Proteinuria is a marker of incipient kidney injury in many disorders, including obesity. Previously, we demonstrated that megalin, a receptor endocytotic protein in the proximal tubule, is downregulated in obese mice, which was prevented by inhibition of dipeptidyl protease 4 (DPP4). Obesity is thou...

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Detalles Bibliográficos
Autores principales: Aroor, Annayya, Zuberek, Marcin, Duta, Cornel, Meuth, Alex, Sowers, James R., Whaley-Connell, Adam, Nistala, Ravi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4881597/
https://www.ncbi.nlm.nih.gov/pubmed/27213360
http://dx.doi.org/10.3390/ijms17050780

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4881597/
https://www.ncbi.nlm.nih.gov/pubmed/27213360
http://dx.doi.org/10.3390/ijms17050780

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