Novel Zinc(II) Complexes [Zn(atc-Et)(2)] and [Zn(atc-Ph)(2)]: In Vitro and in Vivo Antiproliferative Studies

Cisplatin and its derivatives are the main metallodrugs used in cancer therapy. However, low selectivity, toxicity and drug resistance are associated with their use. The zinc(II) (Zn(II)) thiosemicarbazone complexes [Zn(atc-Et)(2)] (1) and [Zn(atc-Ph)(2)] (2) (atc-R: monovalent anion of 2-acetylpyri...

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Detalles Bibliográficos
Autores principales: Lopes, Erica de O., de Oliveira, Carolina G., da Silva, Patricia B., Eismann, Carlos E., Suárez, Carlos A., Menegário, Amauri A., Leite, Clarice Q. F., Deflon, Victor M., Pavan, Fernando R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4881598/
https://www.ncbi.nlm.nih.gov/pubmed/27213368
http://dx.doi.org/10.3390/ijms17050781

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4881598/
https://www.ncbi.nlm.nih.gov/pubmed/27213368
http://dx.doi.org/10.3390/ijms17050781

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