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Calcium phosphate nanoparticles-based systems for siRNA delivery

Despite the enormous therapeutic potential of siRNA as a treatment strategy, the delivery is still a problem due to unfavorable biodistribution profiles and poor intracellular bioavailability. Calcium phosphate (CaP) co-precipitate has been used for nearly 40 years for in vitro transfection due to i...

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Detalles Bibliográficos
Autores principales: Xu, Xiaochun, Li, Zehao, Zhao, Xueqin, Keen, Lawrence, Kong, Xiangdong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4881614/
https://www.ncbi.nlm.nih.gov/pubmed/27252888
http://dx.doi.org/10.1093/rb/rbw010