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RES-529: a PI3K/AKT/mTOR pathway inhibitor that dissociates the mTORC1 and mTORC2 complexes
RES-529 (previously named Palomid 529, P529) is a phosphoinositide 3-kinase (PI3K)/AKT/mechanistic target of rapamycin (mTOR) pathway inhibitor that interferes with the pathway through both mTOR complex 1 (mTORC1) and mTOR complex 2 (mTORC2) dissociation. This compound is currently being developed i...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Lippincott Williams & Wilkins
2016
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4881730/ https://www.ncbi.nlm.nih.gov/pubmed/26918392 http://dx.doi.org/10.1097/CAD.0000000000000354 |