Novel Types of Small RNA Exhibit Sequence- and Target-dependent Angiogenesis Suppression Without Activation of Toll-like Receptor 3 in an Age-related Macular Degeneration (AMD) Mouse Model

RNA interference (RNAi) has become a powerful tool for suppressing gene expression in vitro and in vivo. A great deal of evidence has demonstrated the potential for the use of synthetic small interfering RNAs (siRNAs) as therapeutic agents. However, the application of siRNA to clinical medicine is s...

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Detalles Bibliográficos
Autores principales: Takanashi, Masakatsu, Sudo, Katsuko, Ueda, Shinobu, Ohno, Shin-Ichiro, Yamada, Yuko, Osakabe, Yasuhiro, Goto, Hiroshi, Matsunaga, Yoshimichi, Ishikawa, Akio, Usui, Yoshihiko, Kuroda, Masahiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4881762/
https://www.ncbi.nlm.nih.gov/pubmed/26484944
http://dx.doi.org/10.1038/mtna.2015.34

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4881762/
https://www.ncbi.nlm.nih.gov/pubmed/26484944
http://dx.doi.org/10.1038/mtna.2015.34

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