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Argonaute 2-dependent Regulation of Gene Expression by Single-stranded miRNA Mimics

MicroRNAs (miRNAs) are small noncoding transcripts that regulate gene expression. Aberrant expression of miRNAs can affect development of cancer and other diseases. Synthetic miRNA mimics can modulate gene expression and offer an approach to therapy. Inside cells, mature miRNAs are produced as doubl...

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Detalles Bibliográficos
Autores principales: Matsui, Masayuki, Prakash, Thazha P, Corey, David R
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4881773/
https://www.ncbi.nlm.nih.gov/pubmed/26903376
http://dx.doi.org/10.1038/mt.2016.39