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Argonaute 2-dependent Regulation of Gene Expression by Single-stranded miRNA Mimics
MicroRNAs (miRNAs) are small noncoding transcripts that regulate gene expression. Aberrant expression of miRNAs can affect development of cancer and other diseases. Synthetic miRNA mimics can modulate gene expression and offer an approach to therapy. Inside cells, mature miRNAs are produced as doubl...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4881773/ https://www.ncbi.nlm.nih.gov/pubmed/26903376 http://dx.doi.org/10.1038/mt.2016.39 |