MicroRNA-1301-Mediated RanGAP1 Downregulation Induces BCR-ABL Nuclear Entrapment to Enhance Imatinib Efficacy in Chronic Myeloid Leukemia Cells

Chronic myeloid leukemia (CML) is a myeloproliferative disease. Imatinib (IM), the first line treatment for CML, is excessively expensive and induces various side effects in CML patients. Therefore, it is essential to investigate a new strategy for improving CML therapy. Our immunoblot data revealed...

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Detalles Bibliográficos
Autores principales: Lin, Tsung-Yao, Chen, Ku-Chung, Liu, Hsing-Jin Eugene, Liu, Ann-Jeng, Wang, Kun-Li, Shih, Chwen-Ming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4881950/
https://www.ncbi.nlm.nih.gov/pubmed/27228340
http://dx.doi.org/10.1371/journal.pone.0156260

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4881950/
https://www.ncbi.nlm.nih.gov/pubmed/27228340
http://dx.doi.org/10.1371/journal.pone.0156260

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