Na(+) Influx Induced by New Antimalarials Causes Rapid Alterations in the Cholesterol Content and Morphology of Plasmodium falciparum

Among the several new antimalarials discovered over the past decade are at least three clinical candidate drugs, each with a distinct chemical structure, that disrupt Na(+) homeostasis resulting in a rapid increase in intracellular Na+ concentration ([Na(+)](i)) within the erythrocytic stages of Pla...

Descripción completa

Detalles Bibliográficos
Autores principales: Das, Sudipta, Bhatanagar, Suyash, Morrisey, Joanne M., Daly, Thomas M., Burns, James M., Coppens, Isabelle, Vaidya, Akhil B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4881962/
https://www.ncbi.nlm.nih.gov/pubmed/27227970
http://dx.doi.org/10.1371/journal.ppat.1005647

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4881962/
https://www.ncbi.nlm.nih.gov/pubmed/27227970
http://dx.doi.org/10.1371/journal.ppat.1005647

Ejemplares similares