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Na(+) Influx Induced by New Antimalarials Causes Rapid Alterations in the Cholesterol Content and Morphology of Plasmodium falciparum
Among the several new antimalarials discovered over the past decade are at least three clinical candidate drugs, each with a distinct chemical structure, that disrupt Na(+) homeostasis resulting in a rapid increase in intracellular Na+ concentration ([Na(+)](i)) within the erythrocytic stages of Pla...
Autores principales: | Das, Sudipta, Bhatanagar, Suyash, Morrisey, Joanne M., Daly, Thomas M., Burns, James M., Coppens, Isabelle, Vaidya, Akhil B. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4881962/ https://www.ncbi.nlm.nih.gov/pubmed/27227970 http://dx.doi.org/10.1371/journal.ppat.1005647 |
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