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Glucocorticoids Enhance Muscle Proteolysis through a Myostatin-Dependent Pathway at the Early Stage

Myostatin, a member of the TGF-β superfamily of secreted proteins, is expressed primarily in skeletal muscle. It negatively regulates muscle mass and is associated with glucocorticoid-induced muscle atrophy. However, it remains unclear whether myostatin is involved in glucocorticoid-induced muscle p...

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Detalles Bibliográficos
Autores principales: Wang, Ruxia, Jiao, Hongchao, Zhao, Jingpeng, Wang, Xiaojuan, Lin, Hai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4882021/
https://www.ncbi.nlm.nih.gov/pubmed/27227776
http://dx.doi.org/10.1371/journal.pone.0156225