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Glucocorticoids Enhance Muscle Proteolysis through a Myostatin-Dependent Pathway at the Early Stage
Myostatin, a member of the TGF-β superfamily of secreted proteins, is expressed primarily in skeletal muscle. It negatively regulates muscle mass and is associated with glucocorticoid-induced muscle atrophy. However, it remains unclear whether myostatin is involved in glucocorticoid-induced muscle p...
Autores principales: | Wang, Ruxia, Jiao, Hongchao, Zhao, Jingpeng, Wang, Xiaojuan, Lin, Hai |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4882021/ https://www.ncbi.nlm.nih.gov/pubmed/27227776 http://dx.doi.org/10.1371/journal.pone.0156225 |
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