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Sequential Regulatory Loops as Key Gatekeepers for Neuronal Reprogramming in Human Cells
Direct conversion of somatic cells into neurons holds great promise for regenerative medicine. However, as neuronal conversion is relatively inefficient on human cells compared to mouse cells, it has been unclear what might be key barriers to reprogramming in human cells. We recently elucidated an R...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4882254/ https://www.ncbi.nlm.nih.gov/pubmed/27110916 http://dx.doi.org/10.1038/nn.4297 |