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Sequential Regulatory Loops as Key Gatekeepers for Neuronal Reprogramming in Human Cells

Direct conversion of somatic cells into neurons holds great promise for regenerative medicine. However, as neuronal conversion is relatively inefficient on human cells compared to mouse cells, it has been unclear what might be key barriers to reprogramming in human cells. We recently elucidated an R...

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Detalles Bibliográficos
Autores principales: Xue, Yuanchao, Qian, Hao, Hu, Jing, Zhou, Bing, Zhou, Yu, Hu, Xihao, Karakhanyan, Aziz, Pang, Zhiping, Fu, Xiang-Dong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4882254/
https://www.ncbi.nlm.nih.gov/pubmed/27110916
http://dx.doi.org/10.1038/nn.4297