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MicroRNA-21 is a potential link between non-alcoholic fatty liver disease and hepatocellular carcinoma via modulation of the HBP1-p53-Srebp1c pathway

BACKGROUND: Non-alcoholic fatty liver disease (NAFLD) is a major risk factor for hepatocellular carcinoma (HCC). However, the mechanistic pathways that link both disorders are essentially unknown. OBJECTIVE: Our study was designed to investigate the role of microRNA-21 in the pathogenesis of NAFLD a...

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Detalles Bibliográficos
Autores principales: Wu, Heng, Ng, Raymond, Chen, Xin, Steer, Clifford J, Song, Guisheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4882277/
https://www.ncbi.nlm.nih.gov/pubmed/26282675
http://dx.doi.org/10.1136/gutjnl-2014-308430