Overcoming treatment challenges in myelofibrosis and polycythemia vera: the role of ruxolitinib

Myelofibrosis (MF) and polycythemia vera (PV) are BCR-ABL1-negative myeloproliferative neoplasms associated with somatic hematopoietic stem cell mutations leading to over activation of JAK–STAT signaling. MF and PV are pathogenically related and share specific clinical features such as splenomegaly...

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Detalles Bibliográficos
Autores principales: Bryan, Jeffrey C., Verstovsek, Srdan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2016
Materias:
Review Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4882345/
https://www.ncbi.nlm.nih.gov/pubmed/27017614
http://dx.doi.org/10.1007/s00280-016-3012-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4882345/
https://www.ncbi.nlm.nih.gov/pubmed/27017614
http://dx.doi.org/10.1007/s00280-016-3012-z

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