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Overcoming treatment challenges in myelofibrosis and polycythemia vera: the role of ruxolitinib
Myelofibrosis (MF) and polycythemia vera (PV) are BCR-ABL1-negative myeloproliferative neoplasms associated with somatic hematopoietic stem cell mutations leading to over activation of JAK–STAT signaling. MF and PV are pathogenically related and share specific clinical features such as splenomegaly...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Springer Berlin Heidelberg
2016
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4882345/ https://www.ncbi.nlm.nih.gov/pubmed/27017614 http://dx.doi.org/10.1007/s00280-016-3012-z |