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Tacrolimus Modulates TGF-β Signaling to Induce Epithelial-Mesenchymal Transition in Human Renal Proximal Tubule Epithelial Cells

Epithelial-mesenchymal transition (EMT), a process which describes the trans-differentiation of epithelial cells into motile mesenchymal cells, is pivotal in stem cell behavior, development and wound healing, as well as contributing to disease processes including fibrosis and cancer progression. Mai...

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Detalles Bibliográficos
Autores principales: Bennett, Jason, Cassidy, Hilary, Slattery, Craig, Ryan, Michael P., McMorrow, Tara
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4882479/
https://www.ncbi.nlm.nih.gov/pubmed/27128949
http://dx.doi.org/10.3390/jcm5050050