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Butyrate upregulates endogenous host defense peptides to enhance disease resistance in piglets via histone deacetylase inhibition

Butyrate has been used to treat different inflammatory disease with positive outcomes, the mechanisms by which butyrate exerts its anti-inflammatory effects remain largely undefined. Here we proposed a new mechanism that butyrate manipulate endogenous host defense peptides (HDPs) which contributes t...

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Detalles Bibliográficos
Autores principales: Xiong, Haitao, Guo, Bingxiu, Gan, Zhenshun, Song, Deguang, Lu, Zeqing, Yi, Hongbo, Wu, Yueming, Wang, Yizhen, Du, Huahua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4882515/
https://www.ncbi.nlm.nih.gov/pubmed/27230284
http://dx.doi.org/10.1038/srep27070