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Transcriptome analysis of human ageing in male skin shows mid-life period of variability and central role of NF-κB

Age is well-known to be a significant factor in both disease pathology and response to treatment, yet the molecular changes that occur with age in humans remain ill-defined. Here, using transcriptome profiling of healthy human male skin, we demonstrate that there is a period of significantly elevate...

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Detalles Bibliográficos
Autores principales: Haustead, Daniel J., Stevenson, Andrew, Saxena, Vishal, Marriage, Fiona, Firth, Martin, Silla, Robyn, Martin, Lisa, Adcroft, Katharine F., Rea, Suzanne, Day, Philip J., Melton, Phillip, Wood, Fiona M., Fear, Mark W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4882522/
https://www.ncbi.nlm.nih.gov/pubmed/27229172
http://dx.doi.org/10.1038/srep26846