Exploring the Inhibitory Mechanism of Approved Selective Norepinephrine Reuptake Inhibitors and Reboxetine Enantiomers by Molecular Dynamics Study

Selective norepinephrine reuptake inhibitors (sNRIs) provide an effective class of approved antipsychotics, whose inhibitory mechanism could facilitate the discovery of privileged scaffolds with enhanced drug efficacy. However, the crystal structure of human norepinephrine transporter (hNET) has not...

Descripción completa

Detalles Bibliográficos
Autores principales: Zheng, Guoxun, Xue, Weiwei, Wang, Panpan, Yang, Fengyuan, Li, Bo, Li, Xiaofeng, Li, Yinghong, Yao, Xiaojun, Zhu, Feng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4882549/
https://www.ncbi.nlm.nih.gov/pubmed/27230580
http://dx.doi.org/10.1038/srep26883

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4882549/
https://www.ncbi.nlm.nih.gov/pubmed/27230580
http://dx.doi.org/10.1038/srep26883

Ejemplares similares