Histone methyltransferase Ash1L mediates activity-dependent repression of neurexin-1α

Activity-dependent transcription is critical for the regulation of long-term synaptic plasticity and plastic rewiring in the brain. Here, we report that the transcription of neurexin1α (nrxn1α), a presynaptic adhesion molecule for synaptic formation, is regulated by transient neuronal activation. We...

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Detalles Bibliográficos
Autores principales: Zhu, Τao, Liang, Chen, Li, Dongdong, Tian, Miaomiao, Liu, Sanxiong, Gao, Guanjun, Guan, Ji-Song
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4882582/
https://www.ncbi.nlm.nih.gov/pubmed/27229316
http://dx.doi.org/10.1038/srep26597

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4882582/
https://www.ncbi.nlm.nih.gov/pubmed/27229316
http://dx.doi.org/10.1038/srep26597

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