AMP-activated protein kinase modulates tau phosphorylation and tau pathology in vivo

Neurofibrillary tangles (NFTs) are the pathological hallmark of neurodegenerative diseases commonly known as tauopathies. NFTs result from the intracellular aggregation of abnormally and hyperphosphorylated tau proteins. Tau functions, which include the regulation of microtubules dynamics, are depen...

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Detalles Bibliográficos
Autores principales: Domise, Manon, Didier, Sébastien, Marinangeli, Claudia, Zhao, Haitian, Chandakkar, Pallavi, Buée, Luc, Viollet, Benoit, Davies, Peter, Marambaud, Philippe, Vingtdeux, Valérie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4882625/
https://www.ncbi.nlm.nih.gov/pubmed/27230293
http://dx.doi.org/10.1038/srep26758

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4882625/
https://www.ncbi.nlm.nih.gov/pubmed/27230293
http://dx.doi.org/10.1038/srep26758

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