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The germinal center antibody response in health and disease

The germinal center response is the delayed but sustained phase of the antibody response that is responsible for producing high-affinity antibodies of the IgG, IgA and/or IgE isotypes. B cells in the germinal center undergo re-iterative cycles of somatic hypermutation of immunoglobulin gene variable...

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Detalles Bibliográficos
Autor principal: DeFranco, Anthony L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: F1000Research 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4882753/
https://www.ncbi.nlm.nih.gov/pubmed/27303636
http://dx.doi.org/10.12688/f1000research.7717.1