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The germinal center antibody response in health and disease
The germinal center response is the delayed but sustained phase of the antibody response that is responsible for producing high-affinity antibodies of the IgG, IgA and/or IgE isotypes. B cells in the germinal center undergo re-iterative cycles of somatic hypermutation of immunoglobulin gene variable...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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F1000Research
2016
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4882753/ https://www.ncbi.nlm.nih.gov/pubmed/27303636 http://dx.doi.org/10.12688/f1000research.7717.1 |