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The germinal center antibody response in health and disease

The germinal center response is the delayed but sustained phase of the antibody response that is responsible for producing high-affinity antibodies of the IgG, IgA and/or IgE isotypes. B cells in the germinal center undergo re-iterative cycles of somatic hypermutation of immunoglobulin gene variable...

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Detalles Bibliográficos
Autor principal:	DeFranco, Anthony L.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	F1000Research 2016
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4882753/ https://www.ncbi.nlm.nih.gov/pubmed/27303636 http://dx.doi.org/10.12688/f1000research.7717.1

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