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Non-ionotropic signaling by the NMDA receptor: controversy and opportunity

Provocative emerging evidence suggests that the N-methyl-d-aspartate (NMDA) receptor can signal in the absence of ion flux through the receptor. This non-ionotropic signaling is thought to be due to agonist-induced conformational changes in the receptor, independently of channel opening. Non-ionotro...

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Detalles Bibliográficos
Autores principales: Gray, John A., Zito, Karen, Hell, Johannes W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: F1000Research 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4882754/
https://www.ncbi.nlm.nih.gov/pubmed/27303637
http://dx.doi.org/10.12688/f1000research.8366.1