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Mouse chromosome 2 harbors genetic determinants of resistance to podocyte injury and renal tubulointerstitial fibrosis

BACKGROUND: Tensin2 deficiency results in alterations in podocytes and subsequent glomerular and tubulointerstitial injuries. However, this pathology is critically dependent on genetic background. While the Tensin2-deficient podocytes of resistant murine strains, including C57BL/6J mice, remain almo...

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Detalles Bibliográficos
Autores principales: Sasaki, Hayato, Kimura, Junpei, Nagasaki, Ken-Ichi, Marusugi, Kiyoma, Agui, Takashi, Sasaki, Nobuya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4882790/
https://www.ncbi.nlm.nih.gov/pubmed/27230548
http://dx.doi.org/10.1186/s12863-016-0378-1