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Heat-mediated reduction of apoptosis in UVB-damaged keratinocytes in vitro and in human skin ex vivo

BACKGROUND: UV radiation induces significant DNA damage in keratinocytes and is a known risk factor for skin carcinogenesis. However, it has been reported previously that repeated and simultaneous exposure to UV and heat stress increases the rate of cutaneous tumour formation in mice. Since constant...

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Detalles Bibliográficos
Autores principales: Calapre, Leslie, Gray, Elin S., Kurdykowski, Sandrine, David, Anthony, Hart, Prue, Descargues, Pascal, Ziman, Mel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4882820/
https://www.ncbi.nlm.nih.gov/pubmed/27230291
http://dx.doi.org/10.1186/s12895-016-0043-4