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Systematic interactome mapping of acute lymphoblastic leukemia cancer gene products reveals EXT-1 tumor suppressor as a Notch1 and FBWX7 common interactor

BACKGROUND: Perturbed genotypes in cancer can now be identified by whole genome sequencing of large number of diverse tumor samples, and observed gene mutations can be used for prognosis and classification of cancer subtypes. Although mutations in a few causative genes are directly linked to key sig...

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Detalles Bibliográficos
Autores principales: Daakour, Sarah, Hajingabo, Leon Juvenal, Kerselidou, Despoina, Devresse, Aurelie, Kettmann, Richard, Simonis, Nicolas, Dequiedt, Franck, Twizere, Jean-Claude
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4882867/
https://www.ncbi.nlm.nih.gov/pubmed/27229929
http://dx.doi.org/10.1186/s12885-016-2374-2