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Lysosomal cholesterol accumulation in macrophages leading to coronary atherosclerosis in CD38(−/−) mice
The disruption in transportation of oxLDL‐derived cholesterol and the subsequent lipid accumulation in macrophages are the hallmark events in atherogenesis. Our recent studies demonstrated that lysosomal Ca(2+) messenger of nicotinic acid adenine dinucleotide phosphate (NAADP), an enzymatic product...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
John Wiley and Sons Inc.
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4882979/ https://www.ncbi.nlm.nih.gov/pubmed/26818887 http://dx.doi.org/10.1111/jcmm.12788 |