Cargando…
Lysosomal cholesterol accumulation in macrophages leading to coronary atherosclerosis in CD38(−/−) mice
The disruption in transportation of oxLDL‐derived cholesterol and the subsequent lipid accumulation in macrophages are the hallmark events in atherogenesis. Our recent studies demonstrated that lysosomal Ca(2+) messenger of nicotinic acid adenine dinucleotide phosphate (NAADP), an enzymatic product...
Autores principales: | Xu, Xiaoyang, Yuan, Xinxu, Li, Ningjun, Dewey, William L., Li, Pin‐Lan, Zhang, Fan |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2016
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4882979/ https://www.ncbi.nlm.nih.gov/pubmed/26818887 http://dx.doi.org/10.1111/jcmm.12788 |
Ejemplares similares
-
Simvastatin promotes NPC1‐mediated free cholesterol efflux from lysosomes through CYP7A1/LXRα signalling pathway in oxLDL‐loaded macrophages
por: Xu, Xiaoyang, et al.
Publicado: (2016) -
Downregulation of Lysosomal Acid Ceramidase Mediates HMGB1-Induced Migration and Proliferation of Mouse Coronary Arterial Myocytes
por: Yuan, Xinxu, et al.
Publicado: (2020) -
Use of BODIPY‐Cholesterol (TF‐Chol) for Visualizing Lysosomal Cholesterol Accumulation
por: Hölttä‐Vuori, Maarit, et al.
Publicado: (2016) -
T-cell Cholesterol Accumulation, Aging, and Atherosclerosis
por: Bazioti, Venetia, et al.
Publicado: (2023) -
Autophagy maturation associated with CD38-mediated regulation of lysosome function in mouse glomerular podocytes
por: Xiong, Jing, et al.
Publicado: (2013)