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Aminothiazoles inhibit RANKL‐ and LPS‐mediated osteoclastogenesis and PGE (2) production in RAW 264.7 cells

Periodontitis is characterized by chronic inflammation and osteoclast‐mediated bone loss regulated by the receptor activator of nuclear factor‐κB (RANK), RANK ligand (RANKL) and osteoprotegerin (OPG). The aim of this study was to investigate the effect of aminothiazoles targeting prostaglandin E syn...

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Detalles Bibliográficos
Autores principales: Kats, Anna, Norgård, Maria, Wondimu, Zenebech, Koro, Catalin, Concha Quezada, Hernán, Andersson, Göran, Yucel‐Lindberg, Tülay
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4882984/
https://www.ncbi.nlm.nih.gov/pubmed/26987561
http://dx.doi.org/10.1111/jcmm.12814