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The Inhibitory Effect of Rhein on Proliferation of High Glucose-induced Mesangial Cell Through Cell Cycle Regulation and Induction of Cell Apoptosis

OBJECTIVES: Increased mesangial cell proliferation and accumulation of extracellular matrix (ECM) are the major pathological features of early-stage diabetic nephropathy. This study was sought to investigate the inhibitory effects of rhein (RH) on high glucose (HG)-cultured mesangial cells. Speciall...

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Detalles Bibliográficos
Autores principales: Xu, Shouzhu, Lv, Yanying, Zhao, Jing, Wang, Junping, Wang, Guangjian, Wang, Siwang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4883089/
https://www.ncbi.nlm.nih.gov/pubmed/27279717
http://dx.doi.org/10.4103/0973-1296.182158