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Method dependence, observer variability and kidney volumes in radiation dosimetry of (177)Lu-DOTATATE therapy in patients with neuroendocrine tumours

BACKGROUND: Radionuclide therapy can be individualized by performing dosimetry. To determine absorbed organ doses in (177)Lu-DOTATATE therapy, three methods based on activity concentrations are currently in use: the small volume of interest (sVOI) method, and two methods based on large VOIs either o...

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Detalles Bibliográficos
Autores principales: Sandström, Mattias, Ilan, Ezgi, Karlberg, Anna, Johansson, Silvia, Freedman, Nanette, Garske-Román, Ulrike
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4883125/
https://www.ncbi.nlm.nih.gov/pubmed/26501825
http://dx.doi.org/10.1186/s40658-015-0127-y