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Mannitol Preserves the Viscoelastic Properties of Hyaluronic Acid in an In Vitro Model of Oxidative Stress

INTRODUCTION: Viscosupplementation by intra-articular injection of hyaluronic acid (HA) is a widely used treatment for lower limb osteoarthritis. However, the injected HA is rapidly degraded by reactive oxygen species (ROS), limiting its time of intra-articular residence. Optimizing clinical effecti...

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Detalles Bibliográficos
Autores principales: Conrozier, Thierry, Mathieu, Pierre, Rinaudo, Marguerite
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Healthcare 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4883257/
https://www.ncbi.nlm.nih.gov/pubmed/27747759
http://dx.doi.org/10.1007/s40744-014-0001-8