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A High-Performance Fluorescence Immunoassay Based on the Relaxation of Quenching, Exemplified by Detection of Cardiac Troponin I

The intramolecular fluorescence self-quenching phenomenon is a major drawback in developing high-performance fluorometric biosensors which use common fluorophores as signal generators. We propose two strategies involving liberation of the fluorescent molecules by means of enzymatic fragmentation of...

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Detalles Bibliográficos
Autores principales: Kim, Seung-Wan, Cho, Il-Hoon, Park, Ji-Na, Seo, Sung-Min, Paek, Se-Hwan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4883360/
https://www.ncbi.nlm.nih.gov/pubmed/27171097
http://dx.doi.org/10.3390/s16050669